Stellabody®: A novel hexamer-promoting mutation for improved IgG potency
Whitehead CA, Wines BD, Davies AM, McDonnell JM, Trist HM, Esparon SE, Hogarth PM
Immune Disease + Cancer
Subcutaneous immunotherapy for bee venom allergy induces epitope spreading and immunophenotypic changes in allergen-specific memory B cells.
McKenzie CI, Reinwald S, Averso B, Spurrier B, Satz A, von Borstel A, Masinovic S, Varese N, Aui PM, Wines BD, Hogarth PM, Hew M, Rolland JM, O'Hehir RE, van Zelm MC
Antibody mechanisms of protection against malaria in RTS,S-vaccinated children: a post-hoc serological analysis of phase 2 trial.
Kurtovic L, Feng G, Hysa A, Haghiri A, O'Flaherty K, Wines BD, Santano R, D'Andrea L, Drummer HE, Hogarth PM, Sacarlal J, Fowkes FJI, Simpson JA, Dobaño C, Beeson JG
Malaria
Accurate determination of house dust mite sensitization in asthma and allergic rhinitis through cytometric detection of Der p 1 and Der p 2 binding on Basophils (CytoBas).
Hsin L, Varese N, Aui PM, Wines BD, von Borstel A, Mascarell L, Hogarth PM, Hew M, O'Hehir RE, van Zelm MC.
Robust immunity to influenza vaccination in haematopoietic stem cell transplant recipients following reconstitution of humoral and adaptive immunity.
Zhang W, Rowntree LC, Muttucumaru R, Damelang T, Aban M, Hurt AC, Auladell M, Esterbauer R, Wines B, Hogarth M, Turner SJ, Wheatley AK, Kent SJ, Patil S, Avery S, Morrissey O, Chung AW, Koutsakos M, Nguyen TH, Cheng AC, Kotsimbos TC, Kedzierska K
Mutation of the TGN1412 anti-CD28 Monoclonal Antibody Lower Hinge Confers Specific FcγRIIb Binding and Retention of Super-Agonist Activity.
Chenoweth AM, Esparon S, Wines BD, Schuurman J, Labrijn AF, Hogarth PM
Immune Disease + Cancer