This study is a collaboration between Seattle Children’s Hospital (Principal Investigator: Assistant Prof Heather Jaspan), the Centre for the AIDS Programme of Research in South Africa (Principal Investigator: Associate Professor Jo-Ann Passmore), the University of Cape Town and the Burnet Institute (Principal Investigator: Dr Lindi Masson). It is a longitudinal, observational cohort study including 300 adolescent and 100 adult women in two regions in South Africa (Western Cape and KwaZulu-Natal).
Each woman is being asked to visit the clinic for a baseline visit, followed by four follow-up visits that are timed around sexual activity. Extensive demographic, sexual behaviour, contraceptive use and vaginal hygiene practice data is being collected. Biological factors that are being investigated include the microbiome, HIV target cell phenotype and activation and inflammatory cytokine profiles in the female reproductive tract.
2017–2024
Funding
Partners
- National Institutes of Health
- Carnegie Corporation of New York
- NHMRC
- ACH4
Partners +
Collaborators
- SEATTLE CHILDREN’S HOSPITAL
- UNIVERSITY OF CAPE TOWN
- DESMOND TUTU HEALTH CENTRE
- CENTRE FOR THE AIDS PROGRAMME OF RESEARCH IN SOUTH AFRICA
- UNIVERSITY OF STELLENBOSCH
- UNIVERSITY OF KWAZULU-NATAL
- HUMAN SCIENCES RESEARCH COUNCIL
Project Team
Meet the project team. Together, we are translating research into better health, for all.
