Property activity refinement of 2-anilino 4-amino substituted quinazolines as antimalarials with fast acting asexual parasite activity.
Ashton TD, Ngo A, Favuzza P, Bullen HE, Gancheva MR, Romeo O, Parkyn Schneider M, Nguyen N, Steel RWJ, Duffy S, Lowes KN, Sabroux HJ, Avery VM, Boddey JA, Wilson DW, Cowman AF, Gilson PR, Sleebs BE
Malaria
Defining the Essential Exportome of the Malaria Parasite.
Jonsdottir TK, Gabriela M, Crabb BS, F de Koning-Ward T, Gilson PR
Malaria
Characterisation of complexes formed by parasite proteins exported into the host cell compartment of Plasmodium falciparum infected red blood cells.
Jonsdottir TK, Counihan NA, Modak JK, Kouskousis B, Sanders PR, Gabriela M, Bullen HE, Crabb BS, de Koning-Ward TF, Gilson PR
Malaria
Structure activity refinement of phenylsulfonyl piperazines as antimalarials that block erythrocytic invasion.
Nguyen W, Dans MG, Ngo A, Gancheva MR, Romeo O, Duffy S, de Koning-Ward TF, Lowes KN, Sabroux HJ, Avery VM, Wilson DW, Gilson PR, Sleebs BE
Histone modifications associated with gene expression and genome accessibility are dynamically enriched at Plasmodium falciparum regulatory sequences.
Tang J, Chisholm SA, Yeoh LM, Gilson PR, Papenfuss AT, Day KP, Petter M, Duffy MF
MAM 2020: Growing Strong on the 20th Anniversary
Kaushansky A, Sibley C, McFadden G, Charman S, Doolan D, Good M, Flannery E, Healer J, Duffy M, Taylor T, Craig A, Tilley L, Gilson P
Malaria