Andy Poumbourios

Doctor Andy Poumbourios

Co-Head, Viral Entry and Vaccines Group

Disulfide exchange in domain 2 of CD4 is required for entry of HIV-1.

Matthias LJ, Yam PT, Jiang XM, Vandegraaff N, Li P, Poumbourios P, Donoghue N, Hogg PJ

Disulfide exchange in domain 2 of CD4 is required for entry of HIV-1.

Evidence that the transmembrane domain proximal region of the human T-cell leukemia virus type 1 fusion glycoprotein gp21 has distinct roles in the prefusion and fusion-activated states.

Wilson KA, Maerz AL, Poumbourios P

Evidence that the transmembrane domain proximal region of the human T-cell leukemia virus type 1 fusion glycoprotein gp21 has distinct roles in the prefusion and fusion-activated states.

Functional analysis of the disulfide-bonded loop/chain reversal region of human immunodeficiency virus type 1 gp41 reveals a critical role in gp120-gp41 association.

Maerz AL, Drummer HE, Wilson KA, Poumbourios P

Functional analysis of the disulfide-bonded loop/chain reversal region of human immunodeficiency virus type 1 gp41 reveals a critical role in gp120-gp41 association.

Functional implications of the human T-lymphotropic virus type 1 transmembrane glycoprotein helical hairpin structure.

Maerz AL, Center RJ, Kemp BE, Kobe B, Poumbourios P

Functional implications of the human T-lymphotropic virus type 1 transmembrane glycoprotein helical hairpin structure.

Evolutionary conservation of the membrane fusion machine.

Poumbourios P, Center RJ, Wilson KA, Kemp BE, Kobe B

Evolutionary conservation of the membrane fusion machine.

Crystal structure of human T cell leukemia virus type 1 gp21 ectodomain crystallized as a maltose-binding protein chimera reveals structural evolution of retroviral transmembrane proteins.

Kobe B, Center RJ, Kemp BE, Poumbourios P

Crystal structure of human T cell leukemia virus type 1 gp21 ectodomain crystallized as a maltose-binding protein chimera reveals structural evolution of retroviral transmembrane proteins.

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