An altered and more efficient mechanism of CCR5 engagement contributes to macrophage tropism of CCR5-using HIV-1 envelopes.
Sterjovski J, Roche M, Churchill MJ, Ellett A, Farrugia W, Gray LR, Cowley D, Poumbourios P, Lee B, Wesselingh SL, Cunningham AL, Ramsland PA, Gorry PR
Role for the disulfide-bonded region of human immunodeficiency virus type 1 gp41 in receptor-triggered activation of membrane fusion function.
Bellamy-McIntyre AK, Bär S, Ludlow L, Drummer HE, Poumbourios P
Tissue-specific sequence alterations in the human immunodeficiency virus type 1 envelope favoring CCR5 usage contribute to persistence of dual-tropic virus in the brain.
Gray L, Roche M, Churchill MJ, Sterjovski J, Ellett A, Poumbourios P, Sherieff S, Wang B, Saksena N, Purcell DF, Wesselingh S, Cunningham AL, Brew BJ, Gabuzda D, Gorry PR
Expression and characterization of a minimal hepatitis C virus glycoprotein E2 core domain that retains CD81 binding.
McCaffrey K, Boo I, Poumbourios P, Drummer HE
An N-terminal glycine-rich sequence contributes to retrovirus trimer of hairpins stability.
Wilson KA, Maerz AL, Bär S, Drummer HE, Poumbourios P