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Sialyl-Lewis<sup>X</sup> Glycoantigen Is Enriched on Cells with Persistent HIV Transcription during Therapy.

Colomb F, Giron LB, Kuri-Cervantes L, Adeniji OS, Ma T, Dweep H, Battivelli E, Verdin E, Palmer CS, Tateno H, Kossenkov AV, Roan NR, Betts MR, Abdel-Mohsen M

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  • Journal Cell reports

  • Published 03 May 2021

  • Volume 32

  • ISSUE 5

  • Pagination 107991

  • DOI 10.1016/j.celrep.2020.107991

Abstract

are enriched with markers associated with HIV susceptibility, signaling pathways that drive HIV transcription, and pathways involved in leukocyte extravasation. We describe a glycomic feature of HIV-infected transcriptionally active cells that not only differentiates them from their transcriptionally inactive counterparts but also may affect their trafficking abilities.