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Managing latent tuberculosis infection and tuberculosis in children.

Carvalho I, Goletti D, Manga S, Silva DR, Manissero D, Migliori G

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  • Journal Pulmonology

  • Published 02 Mar 2018

  • Volume 24

  • ISSUE 2

  • Pagination 106-114

  • DOI 10.1016/j.rppnen.2017.10.007

Abstract

Tuberculosis (TB) is a major cause of childhood morbidity and mortality worldwide. The aim of this review is to describe the management of the child with TB and latent tuberculosis infection (LTBI). To develop this article, a working group reviewed relevant epidemiological and other scientific studies and established practices in conducting LBTI and TB in children. The article describes how to manage the child with LTBI, considering transmission and infectiousness of tuberculosis, contact screening and prioritization of contacts and recommendations on treatment of children with LTBI and how to manage the child with TB considering the susceptibility of children to developing tuberculosis, epidemiology and classification of tuberculosis in children, diagnosis and treatment.