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Homologous but not heterologous COVID-19 vaccine booster elicits IgG4+ B-cells and enhanced Omicron subvariant binding.

Hartley GE, Fryer HA, Gill PA, Boo I, Bornheimer SJ, Hogarth PM, Drummer HE, O'Hehir RE, Edwards ESJ, van Zelm MC

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  • Journal NPJ vaccines

  • Published 17 Jul 2024

  • Volume 9

  • ISSUE 1

  • Pagination 129

  • DOI 10.1038/s41541-024-00919-8

Abstract

Bmem after mRNA priming might result from the unique vaccine formulation or dosing schedule affecting the Bmem response duration and antibody maturation.