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Haemophagocytic lymphohistiocytosis secondary to disseminated histoplasmosis in an immunocompetent patient.

Morton M, Vanguru V, Shin JS, Ronnachit A

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  • Journal Medical mycology case reports

  • Published 18 Feb 2024

  • Volume 43

  • Pagination 100635

  • DOI 10.1016/j.mmcr.2024.100635

Abstract

infection is rare and almost always occurs in immunocompromised hosts. We report a 32-year-old immunocompetent man presenting with a nonspecific febrile illness found to have disseminated histoplasmosis and associated haemophagocytic lymphohistiocytosis. The diagnosis was confirmed on histopathological examination and PCR of liver and bone marrow biopsies. He was successfully treated with steroids, intravenous immunoglobulin and itraconazole.