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Frailty in men living with HIV: a cross-sectional comparison of three frailty instruments.

Yeoh HL, Cheng A, Palmer C, Crowe SM, Hoy JF

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  • Journal Antiviral therapy

  • Published 26 Sep 2019

  • Volume 23

  • ISSUE 2

  • Pagination 117-127

  • DOI 10.3851/IMP3185

Abstract

Potent antiretroviral treatment has resulted in near normal life expectancy for people living with HIV. Consequently, there is an increased focus on comorbidities, frailty and quality of life.

We assessed and compared the prevalence of frailty, associated factors and relationship with quality of life in older Australian men living with HIV in a cross-sectional study using three frailty measurements. The Frailty Phenotype, Frailty Index and Edmonton Frail Scale were applied to 93 HIV-infected men aged over 50 years, on antiretroviral therapy. Multivariable ordinal logistic regression was used to analyse the associations of frailty with covariates and quality of life.

T-cell count. Frailty, defined by any of the instruments, was significantly associated with poorer quality of life (P<0.001).

Identifying frailty is an increasingly important contemporary consideration of HIV care related to ageing and quality of life.