The Ophelia (Optimising Health Literacy and Access) process is a systematic approach for improving access to health information and services through health literacy interventions. However, there is limited understanding of how this process can be adapted in low- and- middle-income countries.

A qualitative case study was used to describe how an Ophelia project was designed and introduced in a community setting in the Philippines and to explore the experiences of stakeholders involved in this process. Two qualitative methods were used: document analysis (n = 12) and semi-structured interviews (n = 12).

Data showed that the project stakeholders had embedded the eight Ophelia principles in the design of the project, introduced the Ophelia process in one target community, and conducted a health literacy needs assessment. Project stakeholders faced challenges engaging with local authorities and community members in this location, but overcame these issues through building relationships and understanding their needs. Local authorities and stakeholders provided access to resources and knowledge of this target community.

The Ophelia process can be adapted for a community setting in the Philippines. Understanding local communities is crucial for introducing and engaging participation in this process. SO WHAT?: The Ophelia process may have implications for increasing access to health information and services for vulnerable populations in the Philippines and the Asia Pacific.