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Evidence that the genome of hepatitis A virus consists of single-stranded RNA.

Coulepis AG, Tannock GA, Locarnini SA, Gust ID

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  • Journal Journal of virology

  • Published 23 Jun 1981

  • Volume 37

  • ISSUE 1

  • Pagination 473-7

  • DOI 10.1128/JVI.37.1.473-477.1981

Abstract

Nucleic acid was extracted from purified hepatitis A virus, radiolabeled with 125I, and shown to consist of single-stranded RNA which sediments at 35S and contains sequences of polyadenylic acid. These findings are consistent with hepatitis A virus being a member of the genus Enterovirus within the family Picornaviridae.