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Epitope masking may limit antibody boosting to malaria vaccines.

Kurtovic L, Boyle MJ, Beeson JG

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  • Journal Immunology and cell biology

  • Published 05 Nov 2020

  • Volume 99

  • ISSUE 2

  • Pagination 126-129

  • DOI 10.1111/imcb.12415

Abstract

We discuss the study by McNamara et al., who report that low levels of antigen-specific antibodies in serum can limit the boosting of antibody and B-cell responses following immunization with live attenuated malaria sporozoites.