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Degradation of myxovirus virion RNA by periodate.

Tannock GA, Griffith IP

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  • Journal Intervirology

  • Published 19 Feb 1976

  • Volume 5

  • ISSUE 3-4

  • Pagination 150-61

  • DOI 10.1159/000149892

Abstract

Extensively degraded RNA was isolated from virions of influenza virus which had been oxidized with sodium m-periodate. Similarly, although to a lesser extent, RNA isolated from periodate-treated ribonucleoprotein of influenza virus was also degraded. In contrast, influenza virus RNA, if first freed from other virion components, was not degraded by periodate oxidation.