Publications & Reports

Crystal structures of O-acetylated 2-acylamino-2-deoxy-D-galactose derivatives.

Thomas Mikeska, Martin Nieger, Heidi Mansikkamaki, Jorg Daniels, Thomas Kolter
Kekule-Institut fur Organische Chemie und Biochemie der Universitat, Gerhard-Domagk-Str.1, D-53121 Bonn, Germany.

Abstract

The X-ray structures of 1,3,4,6-tetra-O-acetyl-2-deoxy-alpha-D-galactopyranoside derivatives with four different 2-(acylamino) substituents have been determined with Mo K(alpha) radiation at 123 K. The structure of the 2-acetylamino derivative and of its acyl-homologs with a 2-(propanoylamino)-, 2-(butanoylamino)-, and 2-(2-methyl-propanoylamino)-group crystallized in the monoclinic space group C2. The pyranose unit of all compounds has the usual 4C(1) shape. The different orientations of the 6-O-acetyl-groups are discussed. Conformations of the acylamino-group are compared to those found in the crystal structure of N-acetyl-alpha-D-galactosamine.

Publication

  • Journal: Carbohydrate Research
  • Published: 26/09/2003
  • Volume: 338
  • Issue: 20
  • Pagination: 2119-2128

Author