Abstract
Setting: Gulf Province, a rural area of mainland Papua
New Guinea, is known to have one of the highest burdens of tuberculosis (TB) in the country.
Objectives: To describe the characteristics and outcomes
of TB patients registered for first-line treatment in Kerema
General Hospital in Gulf Province between January and
December 2016.
Design: This was a retrospective cohort study using routinely collected programme data.
Results: Of 347 cases with a recorded TB site, 54% were
male and 32% were aged 15 years. No human immunodeficiency virus (HIV) status was recorded for 51% of
cases. TB was bacteriologically confirmed in 23% of
cases. Among the cohort, there were 145 extrapulmonary TB cases (42%); the site of disease was unknown in
56% of these cases. Of the 297 cases with treatment outcome evaluated, 56% had a favourable outcome and
26% were lost to follow-up. On multivariable analysis, extrapulmonary TB (adjusted OR [aOR] 0.51, 95%CI 0.30–
0.88, P = 0.02) and bacteriologically confirmed TB (aOR
0.40, 95%CI 0.21–0.77, P 0.01) were associated with
decreased odds of an unfavourable treatment outcome.
Conclusion: The study findings highlight the need to
improve TB diagnosis, access to HIV testing, treatment
adherence, patient support and the quality of TB programme data in Gulf Province.
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