Publications & Reports

Adverse events after mass azithromycin treatments for trachoma in Ethiopia.

Berhan Ayele, Teshome Gebre, Jenafir I House, Zhaoxia Zhou, Charles E McCulloch, Travis C Porco, Bruce D Gaynor, Paul M Emerson, Thomas M Lietman, Jeremy D Keenan
The Carter Center, Addis Ababa, Ethiopia.


During a cluster-randomized clinical trial for trachoma in Ethiopia, two rounds of adverse event surveillance were performed in a random sample of communities after community-wide mass azithromycin treatment. The prevalence of any reported adverse event ranged from 4.9% to 7.0% in children 1-9 years of age and from 17.0% to 18.7% in persons >/= 10 years of age. Adverse events appeared to cluster by household and perhaps by village. Mass azithromycin distributions were well tolerated in this setting.


  • Journal: The American Journal of Tropical Medicine and Hygiene
  • Published: 01/08/2011
  • Volume: 85
  • Issue: 2
  • Pagination: 291-294