Publications & Reports

Ribosomal RNA evidence of ocular Chlamydia trachomatis infection following 3 annual mass azithromycin distributions in communities with highly prevalent trachoma.

Jeremy D Keenan, Berhan Ayele, Teshome Gebre, Jeanne Moncada, Nicole E Stoller, Zhaoxia Zhou, Travis C Porco, Charles E McCulloch, Bruce D Gaynor, Paul M Emerson, Julius Schachter, Thomas M Lietman
FI Proctor Foundation, Department of Ophthalmology, University of California, San Francisco, CA 94143-0412, USA. [email protected]


Twelve trachoma-hyperendemic communities were treated with 3 annual mass azithromycin distributions. Children aged 0-9 years were monitored 1 year following the third treatment. An RNA-based test detected ocular chlamydial infection in more children than did a DNA-based test (6.9% vs 4.2%), and in a larger number of communities (8 vs 7).


  • Journal: Clinical Infectious Diseases
  • Published: 15/01/2012
  • Volume: 54
  • Issue: 2
  • Pagination: 253-256