Publications & Reports

Regulatory T-cells: immunomodulators in health and disease.

Scalzo K, Plebanski M, Apostolopoulos V
Vaccine and Infectious Disease Laboratory, Burnet Institute at Austin, Studley Rd, Heidelberg Victoria 3084, Australia.


Regulation of immune responses is crucial in order to maintain immunological self-tolerance. This is maintained in the periphery by a number of cell types that have the capacity to control and regulate immune responses, thus preventing reactivity to self while monitoring appropriate, non-exuberant responses to non-self-antigens. The various mechanisms of regulation will be discussed in this review together with how this knowledge could be used to develop better drugs and treatments for various diseases.


  • Journal: Current Topics in Medicinal Chemistry
  • Published: 01/07/2006
  • Volume: 6
  • Issue: 16
  • Pagination: 1759-1768