Publications & Reports

Hospital practices influence the pattern of infective endocarditis.

D E Dwyer, S C Chen, E J Wright, D Crimmins, P J Collignon, T C Sorrell


OBJECTIVE: To identify factors contributing to infective endocarditis at a major teaching hospital.

METHODS: Retrospective review of clinical records of patients diagnosed with endocarditis by standard case definitions with respect to causative organisms, clinical features and outcome.

RESULTS: One hundred and ninety-three episodes of endocarditis seen between 1979 and 1992 at Westmead Hospital, Sydney, were reviewed. In the 174 cases where the causative organism was isolated, 75 (43%) were Staphylococcus aureus and 50 (29%) were viridans streptococci. Nosocomial acquisition and/or inter-hospital transfer accounted for 83 episodes; 48 (58%) S. aureus (P < 0.001) and nine (11%) viridans streptococci (P < 0.001). In cases from the local community, viridans streptococci were more common than S. aureus (37% versus 25%); these included 18 episodes (14 S. aureus) in intravenous drug users.

CONCLUSION: We conclude that, compared with community-acquired infections, the aetiology of endocarditis in a large teaching hospital is influenced strongly by the prevalence of nosocomial endocarditis and the need for interhospital transfer of complicated cases.


  • Journal: The Medical journal of Australia
  • Published: 06/06/1994
  • Volume: 160
  • Issue: 11
  • Pagination: 709-13, 716