Publications & Reports

The heterosexual HIV type 1 epidemic in Papua New Guinea is dominated by subtype C.

Ryan CE, Gare J, Crowe SM, Wilson K, Reeder JC, Oelrichs RB
The Macfarlane Burnet Institute for Medical Research and Public Health, Melbourne, Victoria, Australia, 3004. claire.ryan@burnet.edu.au

Abstract

Papua New Guinea is in the midst of a generalized HIV epidemic. As part of a larger behavioral survey aiming to further characterize the HIV epidemic occurring in PNG, samples were collected from 1175 participants from seven different provinces. Seventy-one (6%) of these samples were HIV-1 positive, and 35 (49%) successfully underwent a double nested RT-PCR that was designed to amplify the C2-V4 region of the HIV-1 envelope. Sequence analysis showed that 33 (94%) samples were subtype C and the remaining 2 (6%) were subtype B. Further phylogenetic analysis demonstrated that there was no province-specific clustering among the samples and that within the global pandemic, PNG subtype C isolates most closely resembled those from East Africa.

Publication

  • Journal: AIDS Research and Human Retroviruses
  • Published: 01/07/2007
  • Volume: 23
  • Issue: 7
  • Pagination: 941-944

Health Issue