PRIME-TB: Papua New Guinea & Republic of Indonesia for the Micro Elimination of TB

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PRIME-TB will establish four knowledge hubs in in Indonesia (Yogyakarta and Mimika) and Papua New Guinea (Port Moresby and Daru) that can pilot and scale up successful innovations to support the elimination of tuberculosis in these areas. The work includes TB case detection and models of care, and molecular and epidemiological surveillance.


Tuberculosis (TB) remains endemic in the Indo-Pacific region and is the second leading cause of death in both Indonesia and Papua New Guinea (PNG).

At the end of this project, there will be four knowledge hubs in Yogyakarta and Mimika in Indonesia, and Port Moresby and Daru in PNG that can pilot and scale up successful innovations in TB case detection and models of care, and conduct enhanced molecular and epidemiological surveillance, supporting the micro-elimination of TB in these areas.

How the project will achieve its aim

PRIME-TB hubs will be developed as Centres of Excellence within existing Ministry of Health facilities, with resources to mentor TB health workers from across PNG and Indonesia on effective clinical management of TB patients.

Using a continuous quality improvement approach, PRIME-TB will pilot evidence-based TB treatments and innovations to determine their suitability for scaling up to other areas. These pilots will focus on active case finding and preventative treatment, improving access to person-centred care, and access to innovative diagnostics and treatments. Adapted training, toolkits, resources and learning networks for public health leaders and healthcare workers on TB micro-elimination will be developed and rolled out. This will support the strengthening of health workforce capacity to sustain training, adopt innovation and scale-up elimination approaches.

PRIME-TB project staff will use peer education and counselling to raise community awareness of TB health services and generate demand for services that address barriers to accessing care including gender-specific barriers. In addition, the program will work with public health leaders to identify approaches to sustain a concerted effort for TB elimination.

Key laboratories will also be supported to provide rapid molecular testing for TB and TB drug resistance as well as providing data for enhanced surveillance to target TB micro- elimination programs.

How the project has responded to COVID-19

PRIME-TB is supporting the COVID-19 response in across both project countries. In PNG, this includes staff support to the PNG Institute of Medical Research PCR testing laboratory in Port Moresby. Additionally, PRIME-TB has provided assistance to East New Britain through the Provincial Health Authority, supporting COVID-19-focussed community engagement and health education materials.

PRIME-TB partners have been modifying active case finding activities in Yogyakarta to be COVID-19-safe, as well as implementing co-screening for TB and COVID-19. L Evidence on the increased importance and key considerations for active TB case finding during COVID-19 is being generated and shared for broader use.

PRIME-TB Collaborators

Universitas Gadjah Mada, Indonesia Menzies School of Health Research, Australia Papua New Guinea Institute of Medical Research Papua New Guinea national Department of Health and local governments Indonesia national Department of Health and local governments


Australian Government Department of Foreign Affairs and Trade (DFAT) – Centre for Health Security

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March 2020 – June 2023


Universitas Gadjah Mada Partners:Dr Rina Triasih, Dr Bintari Dwihardiani, Dr Betty Nababan, Hastarina Mulia

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Contact Details

For any general enquiries relating to this project, please contact:

Doctor Philipp du Cros

Infectious Diseases Specialist, TB Elimination and Implementation Science