Projects

COVID-19 antigens for PoC test development

We have commenced a large project to express both spike and nucleoprotein of COVID-19, and other coronaviruses - SARS, MERS, OC43, 229E, NL63, and HKU1.

The antigens will be provided to Burnet’s Global Health Diagnostics Development Group for development of a COVID-19 point-of-care (PoC) diagnostic.

Our lab will contribute to PoC test development by providing novel technology to alter antigen structure and enhance sensitivity of PoC tests that can be monitored by Biolayer interferometry.

The Viral Entry and Vaccines Group have extensive expertise in the expression of viral glycoprotein antigens, manipulation of protein sequences to enhance expression and alter folding characteristics and optimisation of purification methods to increase yield and purity.

Timeline

2020 -

Program

Working Group

Staff Members

Funding

Victorian Government (part of $1m for Diagnostics Development)

Health Issue

Contact Details

For any general enquiries relating to this project, please contact:

Professor Heidi E Drummer

Program Director, Disease Elimination; Scientific Director, Burnet Diagnostics Initiative; Head, Global Health Diagnostics Development Laboratory; Co-Head, Drummer/Poumbourios Laboratory

Telephone

+61392822179

Email

[email protected]