Join the fight to achieve global malaria elimination targets
Donate today and join the fight to achieve global malaria elimination targets.
Together we can make a significant contribution to achieving malaria elimination targets.
Donate today and join the fight to achieve global malaria elimination targets.
Together we can make a significant contribution to achieving malaria elimination targets.
Cardiovascular disease (CVD) is a leading cause of death world-wide, and certain populations who experience chronic inflammation, including aged individuals and people living with HIV (PLWH), have an increased risk of CVD. Most CVD starts with a thickening of the artery wall known as atherosclerosis.
We have developed a unique in vitro model of early atherosclerotic events that allows us to study the process of blood monocytes migrating into the blood vessel wall and forming fat-filled cells called “foam cells” which drive atherosclerosis. Using this assay, we have made the novel discovery that monocytes from aged individuals and PLWH have a greater propensity to develop into these atherosclerosis-promoting foam cells, and that this process is heightened by inflammation. What causes this is not known, but we are exploring the following:
2016 – 2019
Associate Professor Anthony Jaworowski, RMIT University Dr Tom Angelovich, RMIT University
For any general enquiries relating to this project, please contact:
Deputy Program Director, Disease Elimination