Projects

A novel gel for targeting vaginal inflammation to prevent HIV transmission

Adolescent girls and young women are disproportionately affected by HIV in sub-Saharan Africa where they are up to 8 times more likely to be infected compared to their male counterparts.

A major biological mechanism driving this increased risk is subclinical genital inflammation due to the presence of “non-optimal” vaginal microbiota depleted of beneficial lactobacillus species.

This study will formulate and perform preclinical safety studies of an anti-inflammatory microbiota metabolite for in-vivo evaluation.

Timeline

2019

Collaborators

Dr Anna Hearps Associate Professor Catriona Bradshaw Dr Simon Cook Dr Simon Moulton Dr Seyoum Ayenhunie

Funding

NHMRC

Contact Details

For any general enquiries relating to this project, please contact:

Professor Gilda Tachedjian

Head of Life Sciences; Head of Tachedjian Laboratory (Retroviral Biology and Antivirals)

Telephone

+61392822256

Email

[email protected]