A novel biomarker for gut leakage as a diagnostic tool for HIV disease progression

Investigating a novel plasma biomarker's potential for identifying gut leakage.

A unique approach to anti-inflammatory immune therapy

Next Generation monoclonal antibody therapies targeting the inhibitory FcR.

Broadly neutralising anti-HIV antibodies and Fc Receptor function

Defining the properties of anti-HIV antibodies for vaccine development and protection of pregnant women.

Developing new HIV disease progression tests

This project will develop prognostic tools to identify HIV+ persons at risk of rapid disease progression.

Discovery of new treatments for myeloma and myelogenous leukemia

We are developing monoclonal antibodies against new biomakers to treat blood cancers.

Getting to the heart of cardiovascular disease in HIV

Investigating the pathogenesis of cardiovascular disease in HIV infection and identifying clinically useful predictors and therapies.

New approaches to the treatment of lupus

Research into an early intervention diagnostic test for Lupus, which is particularly dangerous to women.

Predicting quality and potency of monoclonal and natural antibodies

Rapid, simple and scalable assays for predicting antibody potency.

The impact of viral infections on immune ageing.

Characterising the impact of chronic and acute viral infections on immune ageing, immune dysfunction, and development of age-related diseases.

The role of monocytes in the development of cardiovascular disease

Examining how monocytes drive the thickening of the artery wall.

Understanding the connection between inflammation and cancer

Defining the relationship between inflammation and cancer with the aim of developing new therapies.