Thorey’s PhD project is looking into protein export by the Plasmodium translocon of exported proteins (PTEX) during the asexual blood-stage of the malaria parasite Plasmodium falciparum. PTEX is essential for parasite survival and we need to gain more knowledge on how it operates before we can exploit it as a drug target.
- 2014: BSc University of Iceland
- 2016: BSc (Hons) University of Melbourne
- Spatial organisation of protein export in malaria parasite blood stages.
Charnaud SC, Jonsdottir TK, Sanders PR, Bullen HE, Dickerman BK, Kouskousis B, Palmer CS, Pietrzak HM, Laumaea AE, Erazo AB, McHugh E, Tilley L, Crabb BS, Gilson PR
Traffic. 2018 Apr; 19(8):605-623
- Plasmodium falciparum parasites deploy RhopH2 into the host erythrocyte to obtain nutrients, grow and replicate.
Counihan N, Chisholm SA, Bullen HE, Srivastava A, Sanders PR, Jonsdottir TK, Weiss GE, Ghosh S, Crabb BS, Creek DJ, Gilson PR, de Koning-Ward TF
eLife. 2017 Mar; 6(pii):e23217